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Dr Gareth Forde

Dr Gareth Forde

B.E. (Chemical Engineering, Hons I), University of Queensland, 2000.
Ph.D. (Biochemical Engineering), Cambridge Unit for Bioscience Engineering (CUBE), Department of Chemical Engineering, University of Cambridge, 2004. Grad Cert Higher Education, Monash University, 2007.

Senior Lecturer

Email: Gareth.Forde@eng.monash.edu.au
Tel: +61 3 9905 3437
Fax: +61 3 9905 5686
Room 213, Building 36 Engineering

Research Information Page

Biochemical Engineering Laboratory (BEL)

Professional Appointments

  • 2008- present: Senior lecturer and Bio Engineering Laboratory (BEL) Research Leader, Department of Chemical Engineering, Monash University.
  • 2004 - 2007: VESKI Research Fellow and Lecturer, Department of Chemical Engineering, Monash University.
  • 2001 - 2004: Cambridge Commonwealth Scholar and Research Student, CUBE (Cambridge Unit for Bioscience Engineering), Department of Chemical Engineering, University of Cambridge.
  • 2000: Surveillance engineer, Esso Australia Ltd.

Professional Affiliations 

  • MIChemE
  • MRSC
  • Chartered Engineer (CEng), Engineering Council UK.
  • Chartered Scientist (CSci), The Science Council.
  • Junior Fellow of the Cambridge Commonwealth Society.

Current Research and Professional Interests 

  • Biochemical and bioprocess engineering.
  • Solid phase adsorbent and ligand design for biomolecule purification.
  • Vaccine production, encapsulation and delivery: DNA and plant made vaccines.
  • Protein/DNA affinity interactions.
  • Design of multifunctional particles for biomolecule encapsulation & delivery.
  • Ultrasonic atomization for the creation of nano and micro particles.
  • Fermentation science: Optimization of fed bath operations for the expression of bio-pharmaceuticals and recombinant proteins.
  • Renewable energy from cellular systems.
  • Cell culture dewatering.
  • Lipid extraction from algae

Selected Publications and Presentations

  • Darby, R.A.J., Forde, G.M., Slater, N.K.H. and Hine, H.V., “Affinity Purification of Plasmid DNA Directly from Crude Bacterial Cell Lysates”, BIOTECHNOLGY AND BIOENGINEERING, accepted 30th April 2007, DOI 10.1002/bit. 21492.
  • Danquah, M.K. and Forde, G.M., “Enhancing methacrylate-monolith-based downstream processes to champion plasmid DNA production”, BIOTECHNOLGY AND APPLIED BIOCHEMISTRY, 48: 85-91 (2007).
  • Ho, J., Danquah, M., Wang, H., and Forde, G.M., “Protein Loaded Mesoporous Silica Spheres as a Controlled Delivery Platform”, JOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, accepted 28th Sept 2007.
  • Danquah, M.K. and Forde, G.M., “Growth medium selection and economic consideration for plasmid DNA production”, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, accepted 27th Sept 2007, https://55099zzwd.coop.osaka-u.ac.jp/JRS/upload/070926-44d2a9cfc1d13c754a73e7d7de3ca4ad_manuscript.pdf.
  • Danquah, M.K., Ho, J., and Forde, G.M., “Performance of R-N(R9)-R99 functionalised poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) monolithic sorbent for plasmid DNA adsorption”, JOURNAL OF SEPARATION SCIENCE, 30, accepted 27th Sept 2007.
  • Danquah, M.K. and Forde, G.M., “The suitability of DEAE-Cl active groups on customized poly(GMA-co-EDMA) continuous stationary phase for fast enzyme-free isolation of plasmid DNA", JOURNAL OF CHROMATOGRAPHY B, Vol 856 (1-2): 386-386 (2007).
  • Ho, J., Zhu, W., Wang, H., Forde, G.M., “Mesoporous silica spheres from colloids”, JOURNAL OF COLLOID AND INTERFACE SCIENCE, Vol 308(2): 374-380 (2007).
  • Danquah, M.K. and Forde, G.M., “Towards the design of a scalable and commercially-viable technique for plasmid purification using a methacrylate monolithic stationary phase”, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, accepted for publication 19th Feb 2007.
  • Forde, G.M., Williamson, T., & Friend, J., “Straightforward Biodegradeable Nanoparticle Generation through MHz-order Ultrasonic Atomization”, APPLIED PHYSICS LETTERS, 89: 064105 (2006).
  • Forde, G.M., Ghose, S., Slater, N.K.H., Hine, A.V., Darby, R.A.J., & Hitchcock, A.G., ‘LacO-LacI Interaction in Affinity Adsorption of Plasmid DNA’, BIOTECHNOLGY AND BIOENGINEERING, Vol 95(1): 67-75 (2006).
  • Forde, G.M., Coomes, A.D., Giliam, F.K., Han, Y., & Horsfall, M.J., ‘Creation of protein loaded biodegradable microparticles via ultrasonic atomisation suitable for nasal delivery’, CHEMICAL ENG RESEARCH & DESIGN, 84(A3): 178–184 (2006).
  • Danquah, M.K. and Forde, G.M., ‘Rapid therapeutic plasmid DNA isolation: Addressing the looming vaccine crisis’, BIOFORUM EUROPE, ISSN 1611-597X, 10: 24 – 27 (2006).
  • Forde, G.M., 'Rapid-response vaccines - does DNA offer a solution?', NATURE BIOTECHNOLOGY, Vol 23(9): 1059-1062 (2005).
  • Ghose, S., Forde, G.M., and Slater, N.K.H., “Affinity Adsorption of Plasmid DNA”, BIOTECHNOLOGY PROGRESS, Volume 20(3), 841-850, 2004.
  • MC8 (RSC Materials Chemistry Conference), University College London, UK. “Inorganic-polymer composite particles for staged vaccine delivery via nasal inhalation”, 2007.
  • CHEMECA 2007, Melbourne. “Production of Nano and Micro Particles via Ultrasonication for Biopharmaceutical Delivery”, 2007.
  • Nanomed Conference, Newcastle Upon Tyne/University of Newcastle, UK. “Creation of micro and nanoparticles via ultrasonic atomisation for enhanced biopharmaceutical delivery”, 2006.
  • Fermentation and Bioprocessing National Conference, Melbourne. “Production and Purification of Plasmid DNA”, Organised by Fermentation & Bioprocessing Interest Group, AusBiotech, 2006.
  • Bioscience Engineering Seminar Series, Cambridge University. “Downstream Purification and Controlled Delivery of Biomolecules”, 2006.
  • AIChE Annual Meeting, Cincinnati, USA. “Plasmid DNA Purification and Formulation for Vaccine Applications” (co-authored by Dr. James Friend), 2005.
  • Alfred Deakin Innovation Lecture Series, Melbourne. “Healthy Relations - Does DNA Offer a Solution to the Vaccine Crisis?”, 2005.
  • BioMelbourne Network, Melbourne. “Biotech facilities of the future - the key to 21st century infrastructure”, 2005.
  • Symposium of the Centre for Nanostructural Bioengineering, Gold Coast. “The Vaccine Crisis: Does DNA Offer a Solution?”, 2005.
  • Younger European Chemists Conference, Grenoble, France. “Protein mediated affinity purification of plasmid DNA”, 2003.
  • Biochemical Engineering Research Network Meeting, Cambridge, UK. “Affinity Purification of Plasmid DNA”, 2002.
  • European Symposium on Biochemical Engineering Science, Delft, Netherlands. “Plasmid DNA Purification”, 2002.