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Dr Gareth Forde
B.E. (Chemical Engineering, Hons I), University of Queensland,
2000.
Ph.D. (Biochemical Engineering), Cambridge Unit for Bioscience
Engineering (CUBE), Department of Chemical Engineering, University of
Cambridge, 2004.
Grad Cert Higher Education, Monash University, 2007.
Senior Lecturer
email: gareth.forde@eng.monash.edu.au
Tel: +61 3 9905 1995
Fax: +61 3 9905 5686
Room 214, Building 36 Engineering
Research Information Page
Biochemical Engineering
Laboratory (BEL)
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Professional Appointments
- 2008- present: Senior lecturer and Bio Engineering Laboratory (BEL)
Research Leader, Department of Chemical Engineering, Monash University.
- 2004 - 2007: VESKI Research Fellow and Lecturer, Department of
Chemical Engineering, Monash University.
- 2001 - 2004: Cambridge Commonwealth Scholar and Research Student, CUBE
(Cambridge Unit for Bioscience Engineering), Department of Chemical
Engineering, University of Cambridge.
- 2000: Surveillance engineer, Esso Australia Ltd.
Professional Affiliations
- MIChemE
- MRSC
- Chartered Engineer (CEng), Engineering Council UK.
- Chartered Scientist (CSci), The Science Council.
- Junior Fellow of the Cambridge Commonwealth Society.
Current Research and Professional Interests
- Biochemical and bioprocess engineering.
- Solid phase adsorbent and ligand design for biomolecule purification.
- Vaccine production, encapsulation and delivery: DNA and plant made
vaccines.
- Protein/DNA affinity interactions.
- Design of multifunctional particles for biomolecule encapsulation &
delivery.
- Ultrasonic atomization for the creation of nano and micro particles.
- Fermentation science: Optimization of fed bath operations for the
expression of bio-pharmaceuticals and recombinant proteins.
- Renewable energy from cellular systems.
- Cell culture dewatering.
- Lipid extraction from algae
Selected Publications and Presentations
- Darby, R.A.J., Forde, G.M., Slater, N.K.H. and Hine, H.V., “Affinity
Purification of Plasmid DNA Directly from Crude Bacterial Cell Lysates”,
BIOTECHNOLGY AND BIOENGINEERING, accepted 30th April 2007, DOI
10.1002/bit. 21492.
- Danquah, M.K. and Forde, G.M., “Enhancing methacrylate-monolith-based
downstream processes to champion plasmid DNA production”, BIOTECHNOLGY AND
APPLIED BIOCHEMISTRY, 48: 85-91 (2007).
- Ho, J., Danquah, M., Wang, H., and Forde, G.M., “Protein Loaded
Mesoporous Silica Spheres as a Controlled Delivery Platform”, JOURNAL OF
CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, accepted 28th Sept 2007.
- Danquah, M.K. and Forde, G.M., “Growth medium selection and economic
consideration for plasmid DNA production”, JOURNAL OF BIOSCIENCE AND
BIOENGINEERING, accepted 27th Sept 2007,
https://55099zzwd.coop.osaka-u.ac.jp/JRS/upload/070926-44d2a9cfc1d13c754a73e7d7de3ca4ad_manuscript.pdf.
- Danquah, M.K., Ho, J., and Forde, G.M., “Performance of R-N(R9)-R99
functionalised poly(glycidyl methacrylate-co-ethylene glycol
dimethacrylate) monolithic sorbent for plasmid DNA adsorption”, JOURNAL OF
SEPARATION SCIENCE, 30, accepted 27th Sept 2007.
- Danquah, M.K. and Forde, G.M., “The suitability of DEAE-Cl active
groups on customized poly(GMA-co-EDMA) continuous stationary phase for
fast enzyme-free isolation of plasmid DNA", JOURNAL OF CHROMATOGRAPHY B,
Vol 856 (1-2): 386-386 (2007).
- Ho, J., Zhu, W., Wang, H., Forde, G.M., “Mesoporous silica spheres
from colloids”, JOURNAL OF COLLOID AND INTERFACE SCIENCE, Vol 308(2):
374-380 (2007).
- Danquah, M.K. and Forde, G.M., “Towards the design of a scalable and
commercially-viable technique for plasmid purification using a
methacrylate monolithic stationary phase”, JOURNAL OF CHEMICAL TECHNOLOGY
AND BIOTECHNOLOGY, accepted for publication 19th Feb 2007.
- Forde, G.M., Williamson, T., & Friend, J., “Straightforward
Biodegradeable Nanoparticle Generation through MHz-order Ultrasonic
Atomization”, APPLIED PHYSICS LETTERS, 89: 064105 (2006).
- Forde, G.M., Ghose, S., Slater, N.K.H., Hine, A.V., Darby, R.A.J., &
Hitchcock, A.G., ‘LacO-LacI Interaction in Affinity Adsorption of Plasmid
DNA’, BIOTECHNOLGY AND BIOENGINEERING, Vol 95(1): 67-75 (2006).
- Forde, G.M., Coomes, A.D., Giliam, F.K., Han, Y., & Horsfall, M.J.,
‘Creation of protein loaded biodegradable microparticles via ultrasonic
atomisation suitable for nasal delivery’, CHEMICAL ENG RESEARCH & DESIGN,
84(A3): 178–184 (2006).
- Danquah, M.K. and Forde, G.M., ‘Rapid therapeutic plasmid DNA
isolation: Addressing the looming vaccine crisis’, BIOFORUM EUROPE, ISSN
1611-597X, 10: 24 – 27 (2006).
- Forde, G.M., 'Rapid-response vaccines - does DNA offer a solution?',
NATURE BIOTECHNOLOGY, Vol 23(9): 1059-1062 (2005).
- Ghose, S., Forde, G.M., and Slater, N.K.H., “Affinity Adsorption of
Plasmid DNA”, BIOTECHNOLOGY PROGRESS, Volume 20(3), 841-850, 2004.
- MC8 (RSC Materials Chemistry Conference), University College London,
UK. “Inorganic-polymer composite particles for staged vaccine delivery via
nasal inhalation”, 2007.
- CHEMECA 2007, Melbourne. “Production of Nano and Micro Particles via
Ultrasonication for Biopharmaceutical Delivery”, 2007.
- Nanomed Conference, Newcastle Upon Tyne/University of Newcastle, UK.
“Creation of micro and nanoparticles via ultrasonic atomisation for
enhanced biopharmaceutical delivery”, 2006.
- Fermentation and Bioprocessing National Conference, Melbourne.
“Production and Purification of Plasmid DNA”, Organised by Fermentation &
Bioprocessing Interest Group, AusBiotech, 2006.
- Bioscience Engineering Seminar Series, Cambridge University.
“Downstream Purification and Controlled Delivery of Biomolecules”, 2006.
- AIChE Annual Meeting, Cincinnati, USA. “Plasmid DNA Purification and
Formulation for Vaccine Applications” (co-authored by Dr. James Friend),
2005.
- Alfred Deakin Innovation Lecture Series, Melbourne. “Healthy Relations
- Does DNA Offer a Solution to the Vaccine Crisis?”, 2005.
- BioMelbourne Network, Melbourne. “Biotech facilities of the future -
the key to 21st century infrastructure”, 2005.
- Symposium of the Centre for Nanostructural Bioengineering, Gold Coast.
“The Vaccine Crisis: Does DNA Offer a Solution?”, 2005.
- Younger European Chemists Conference, Grenoble, France. “Protein
mediated affinity purification of plasmid DNA”, 2003.
- Biochemical Engineering Research Network Meeting, Cambridge, UK.
“Affinity Purification of Plasmid DNA”, 2002.
- European Symposium on Biochemical Engineering Science, Delft,
Netherlands. “Plasmid DNA Purification”, 2002.
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